Turmeric (CURCUMA LONGA LINN.) Rhizome Extract: Its Antiinflammatory Effect Using CHORIOALLANTOIC MEMBRANE (CAM) Assay

Nelsa  Maradul,

Turmeric (CURCUMA LONGA LINN.) Rhizome Extract: Its Antiinflammatory Effect Using CHORIOALLANTOIC MEMBRANE (CAM) Assay

Abstract:

Turmeric (Curcuma longa Linn.) is a herbaceous plant member of the ginger family (Zingiberaceae) which is widely known in the Philippines for its uses in culinary as a spice and scientific world as a herbal plants. Turmeric is scientifically proven to have antioxidant, antiinflammatory, and anti-cancer effect.Turmeric has a lot benefit when it comes to health, as it can help in the management of inflammatory conditions arthritis, anxiety, and hyperlipidemia. It can also help in management of exercise induced inflammation and muscle soreness, thus enhancing recovery and subsequent performance in active people.The study aimed to determine the anti-inflammatory effect of Turmeric (Curcuma longa Linn.) by Chorioallantoic Membrane Assay. The Chorioallantoic Membrane Assay is method that uses duck embryo through incubation process. The study was experimentally conducted using various procedures from phytochemical screening of the plants, preparation of the materials and plant samples, incubation of duck egg, ethanolic extraction, and CAM Assay. The anti-inflammatory effect of two test solutions, 100% and 75% concentration showed significant difference wherein 100% concentration of test solution resulted in a commutative score of 5.67 which is interpreted as having moderate irritation. While the 75% concentration of test solution has a commutative score of 3.90 which interpreted as slight irritation. Therefore, 75% concentration of test solution has lesser changes in irritation on CAM Assay test. The commercially available drug Diclofenac sodium 25mg/1mL with the mean of 0.80 interpreted as partially none. the findings revealed, the 75% concentration and Diclofenac sodium are statistically high significant.

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